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  • PositionSalaryNumberWork experienceRelease timeApply
  • Director/Senior Director – Immuno-Oncology Department HeadNegotiable23 years2018-01-30Apply
    Responsibilities:

    1.Ph.D. and/or MD inImmunology/cancer biology/Biochemistry or related biology discipline, with 3-5years of post doctoral translational research experience in tumorimmunology/protein therapeutics.
    2.Hands on experience and strong expertise in T-cell/B-cell/NK-cell biology,molecular biology, cancer models.
    3.Demonstrated proficiency in performing and/or developing various Cell biology, Hematology, and Immunology related techniques and methodologies whichinclude ELISA, cell purification/culture, proliferation, multicolor flowcytometry etc.
    4.Industrial experience in drug discovery is desirable. Good written and verbalcommunication skills, strong capability in technical trouble shooting.
    5.The candidate will work with a vibrant and multi-disciplinary group. Must beable to motivate fellow team members and work with passion and enthusiasm oncancer research and development.

    Qualifications:

    1.Strategically managesimmune-oncology resources to meet discovery goals for the oncology portfolio(R&D pipelines).
    2.Represent Immuno-Oncology project team; key contributor to YZY Biopharmastrategies.
    3.Play a leadership role within the discipline and contribute to direction andstrategies for both the cancer pharmacology and immunology science. Responsiblefor providing scientific input, oversight, and study execution regardingdesign, conducts and interpretation of lab experiments to evaluate candidatebiotherapeutics to advance programs in the oncology portfolio.
    4.Identify and validate new cancer drug targets, develop and perform primaryand secondary biological assays, and conduct cell-based assays to guidepreclinical studies.
    5.Plan, implement and manage in vivo activities (efficacy, safety and PK/PD) todeliver key data package to support MOA characterization and drug candidateselection.

  • Principal Investigator (Department of Antibody Technology) Negotiable23 years2018-01-30Apply
    Responsibilities:

    3+ years of post-degreeresearch experience in antibody/ protein therapeutics. The idea candidate musthave an established record of innovative research in antibody therapeutics.Must be independent, creative, and self-motivated. Should have hands on in-depthexperience in Molecular Biology, lead antibody discovery and optimization,generation of chimeric and humanized antibody and protein engineering.  Past supervisory experience is stronglypreferred.

    Qualifications:

    We are seeking a highlymotivated individual to join and lead the antibody technology group to supporttherapeutic antibody programs. The major responsibilities of this position willbe focusing on lead antibody discovery, generation of chimeric and humanizedantibody, affinity maturation, Protein engineering, and novel technologydevelopment for antibody/protein therapeutics. The ideal candidate must havein-depth knowledge in therapeutic antibody field plus molecular cloning, mustbe well organized with excellent interpersonal and oral/written communicationskills, and be able to manage research projects .independently.

  • Senior Scientist Of Process DevelopmentNegotiable110 years2018-01-30Apply
    Responsibilities:

    1.PhD with 10+ yearsindustry experience or MS with 15+ years industry experience in BiochemicalEngineering, Chemical Engineering, Biochemistry or related field.
    2.Hands-on experience with CHO and other mammalian cell for mAb or recombinantprotein production is required.
    3.Hands-on experience in bioreactor purification is required.
    4.Previous experience in cell culture scale-up, tech transfer includingdrafting development reports, protocols etc., is highly desired.
    5.Previous experience in process development and optimization using statisticaltools is a plus (DOE and data analysis).
    6.The ability to succeed in a multidisciplinary, fast changing and diverse teamenvironment.
    7.Independent thinking and good communication and problem solving skills.
    8.Fluent communication in English and Chinese is a plus.

    Qualifications:

    1.Supervise daily Processactivities and ensure production timelines are met.
    2.Develop & optimize processes for IND-enabling projects perChina/US/regulatory requirements.
    3.Lead a group of scientists and engineers to develop cell line, cell culture,purification process, scale-up , pilot scale productin and formulation for mAbsor recombinant protein production.
    4.Design and carry out experiments at bench and pilot scale and providetechnical leadership to associates.
    5.Contributes to continual improvement of all development documentation (SOP’s) to ensure they are current, accurate, and clear.
    6.Explore new technologies to speed up process development.
    7.Collaborate with other functional groups on the projects such as, R&Dgroup, and analytical group, etc.
    8.Motivate, retain, develop, train group members and recruit new staffs tobuild a strong team.

  • BD Director/ManagerNegotiable11 years2018-01-30Apply
    Responsibilities:

    1.Trust worthy. Ability towork well across client organization ( from top management to front line staff); demonstrated leadership and working well in a team.
    2.Open minded and willing to learn by him/herself to expand horizon.
    3.Science, Engineering, Marketing, Medical background; Tumor drug developmentexperience preferred.
    4.Ability to see the big picture and to execute.
    5.Good English skill.

    Qualifications:

    1.Keep abreast of globalpharma/biotech industry development, emerging trend, new innovative technology,competitive landscape, and overall tumor drug development value chain.
    2.Developing BD strategy plan for YZY based on YZY strategy, business, andfinancial evaluation focusing on antibody drug development.
    3.Responsible for full range of end-to-end BD activities, includingscouting/deal sourcing, engagement, evaluation, due diligence, negotiation,execution.
    4.Manage 3rd party relationships including academic, biotech, CRO/CMO, pharmaglobally and in China.
    5.Lead cross functional team to execute on complex business deals.
    6.Other responsibilities include government relations, industry trends andfinancial evaluation, fund raising, technology assessment, KOL engagement,access and pricing strategy, etc as needed.

  • Cell Line Development Senior/ Senior ScientistNegotiable13 years2018-01-30Apply
    Responsibilities:

    1.Ph.D. in Molecular and/orCellular Biology, Biochemistry, Pharmaceutical Sciences, Chemical Engineeringor a related field.
    2.3+ years experience in the biopharmaceutical or biotech industry.
    3.In-depth knowledge of biopharmaceuticals principles.
    4.Working knowledge of bioprocess development and/or technology transfer is aplus.
    5.Knowledge in GMPs, ICH guidelines is preferred.
    6.Excellent communication skills both in writing and oral presentation.
    7.Excellence in organizational, interpersonal, communication skills and withstrong problem-solving capability.

    Qualifications:

    1.Technical lead for cellline development for biologic development.
    2.Lead to develop molecular and cellular techniques for high expression systemfor antibody-based biologics.
    3.Responsible for productivity of the CLD team.
    4.Quick adapt to new technology and be a technical leader in CLD-related areas.
    5.Write technical project reports and prepare document for cFDA and FDA INDfilling.
    6.Work closely with R & D and upstream teams for tech transfer.
    7.May lead project and matrix team meetings and coordinate activities withinCMC teams.

  • Downstream Process Development Manger/Senior ManagerNegotiable13 years2018-01-30Apply
    Responsibilities:

    1.MS with 5+ years, or PhDwith 3+ years bioprocess development experience in a biopharmaceutical orbiotechnological industrial.
    2.3+ Years working experience in developing large-scale chromatography, harveststep, ultrafiltration/diafiltration, and viral inactivation and removal.
    3.Working experience in bioprocess scale-up and technology transfer.
    4.Knowledge in cGMPs, and ICH guidelines is preferred.
    5.Working experience of Design of Experiments.
    6.With strong problem-solving capability.
    7.Excellence in organizational, interpersonal, and communication skills.

    Qualifications:

    1. Design and developbiologic downstream processes that are efficient, robust and scalable for themanufacturing.
    2.Lead downstream process development team, response for their daily works,training and maintaining the team to reach high productivity.
    3.Establish robust purification development and scale-up platforms for biologicdevelopment.
    4.Write technical project reports and prepare document for cFDA and FDA INDfilling.
    5.Work closely with upstream bioprocess and production teams for tech transferand scaling up.
    6.Lead project and matrix team meetings and coordinate activities within theproject teams.

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